Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T4259 |
GLPG0187
|
Integrin | Cytoskeletal Signaling |
GLPG0187是整联蛋白受体的广谱拮抗剂,抑制αvβ1-integrin 的IC50值为1.3 nM,具有抗肿瘤活性。 | |||
T68270 |
Avutometinib potassium
|
||
Avutometinib potassium is a MEK inhibitor (MEKi) that enhanced the inhibition of pseudovirus infection by GLPG-0187. It Blocks SARS-CoV-2 Delta and Omicron Pseudovirus Infection of Airway Epithelial Cells In Vitro, Which Could Attenuate Disease Severity |